photo of Ray Sachs

Rainer Sachs, PhD

Adjunct Research Professor of Medicine
Center of Cancer Systems Biology

Professor Emeritus of Mathematics and Physics
Research Professor of Mathematics
University of California, Berkeley

Ray maintains a webpage at UC Berkeley.

Education and Training:

Positions and Honors:

1962 – 63 Assistant Professor, Dept. Physics, Stevens Institute of Technology, Hoboken NJ
1963 – 66 Associate Professor, Dept. Physics, University of Texas at Austin
1966 Guggenheim Fellowship
1966 – 68 Professor, Dept. Physics, University of Texas at Austin
1969 – 92 Professor, Depts. Physics and Mathematics, University of California at Berkeley
2005 – 15 Adjunct Professor, Tufts University School of Medicine
1993 – Professor Emeritus, Dept. Physics and Dept. Mathematics, University of California at Berkeley
1993 – Research Professor of Mathematics, University of California at Berkeley
2008 – Editorial Board, Biology Direct, Mathematical Biology

Recently Completed Research Support:

DOE/Office of Science: BER (PI: P. Hahnfeldt; Consultant: R. Sachs)   7/2009 – 7/2013
Intercellular Interactions during Tumor Progression: Implications for Low-Dose Risk.
The goal of the grant is to analyze the implications of intercellular interactions on ionizing-radiation induced cancer risks at low and very low doses. Such interactions call into question a standard microdosimetric argument for risk linearity; a key question is to estimate in which direction the possible deviations from linearity may be.

NASA | NSCOR 04-0014-0017 / NNJ04HJ12G / NNJ06HA28G (PI: L. Hlatky; Asst. Dir.: R. Sachs)   10/1/2004 – 10/31/2010
NSCOR: Solid Tumor Risk Estimation: Incorporating Intercellular Interaction Effects.
The goal of the overall grant is to study radiation solid tumor risk to astronauts on an extended space mission, experimentally and mathematically. A Berkeley subcontract (PI: Sachs) emphasizes microdosimetry and the role of chromosome aberrations in carcinogenesis.

NIH | RO1 GM 068423 (PI: R. Sachs)   7/1/2003 – 6/30/2008
Updating Chromosome Aberration Simulator (CAS) Software.
Main goals were to make CAS freely available to the radiation cytogenetics community and to extend it.

DOE | DE-FG02-03ER63668 (PI: R. Sachs)   09/1/2003 – 8/31/2007
Modeling Interellations Between the Bystander Effect, Chromosomal Instability, and Radiation Risk.
The major goal of this project was to model signaling in the radiation bystander effect and low-dose cancer risk, using mathematical formalisms and computer simulations.

Selected Publications: