photo of Roberto Pola

Roberto Pola, MD, PhD


Associate Investigator
Center of Cancer Systems Biology

Adjunct Assistant Professor of Medicine
Tufts University School of Medicine


Mail: roberto.pola [at] tufts.edu

Education and Training:

Academic Positions:

1999 – 2001 Research Fellow, Division of Cardiovascular Research, St. Elizabeth's Medical Center, Boston, MA (Mentor: Dr. Jeffrey M. Isner)
2001 – 2003 Research and Clinical Fellow, Center of Medicine and Research on Aging, A. Gemelli University Hospital in Rome, Italy
2005 – 2008 Assistant Professor, Department of Anatomy and Cell Biology, Tufts University School of Medicine, Boston, MA
2008 – 2010 Associate Investigator, Division of Cardiovascular Research, St. Elizabeth's Medical Center, Boston, MA
2004 – current Assistant Professor, Department of Medicine of the Catholic University School of Medicine, Rome, Italy
2008 – current Adjunct Assistant Professor, Department of Medicine, Tufts University School of Medicine, Boston, MA
2011 – current Associate Investigator, Center of Cancer Systems Biology, Boston, MA

Awards and Honors:

2000 Travel Stipend Award for Young Investigators of the Council on Arteriosclerosis, Thrombosis and Vascular Biology at the 73rd Scientific Sessions of the American Heart Association (AHA), New Orleans, LA, USA
2001 Young Investigator Award at the 18th Conference of the International Society of Thrombosis and Haemostasis (ISTH), Paris, France
2001 Melvin L. Marcus Young Investigator Award in Cardiovascular Sciences at the 74th Scientific Sessions of the American Heart Association (AHA), Anaheim, CA, USA
2004 – 2011 D1 Awards, Catholic University School of Medicine, Rome, Italy
2009 Charlton Family Foundation Award, Tufts University School of Medicine, Boston, MA, USA
2010 Annual Research Day Award, 1st Prize in the Basic Science Category, St. Elizabeth's Medical Center, Boston, MA, USA
2010 Annual Research Day Award, 2nd Prize in the Clinical/Translational Science Category, St. Elizabeth’s Medical Center, Boston, MA, USA
2012 Young Investigator Award, Italian Department of Health

Scientific Activity:

Dr. Pola has published more than 80 papers in peer-reviewed scientific journals, including Nature, Nature Medicine, Nature Genetics, J Clin Invest, Circulation, J Am Coll Cardiol, Diabetes, Molecular Therapy, and ATVB.

He has received grants from the NIH, the Italian Ministry of University and Research (MIUR), the Italian Department of Health, Tufts University, and the Catholic University School of Medicine, Rome, Italy. He is a member of the Review Board of the Italian Society of Internal Medicine, the Italian Department of University and Scientific Research (MIUR), the Italian Department of Health, the Diabetes-UK Foundation, the British Diabetic Association, and the French Muscular Dystrophy Association (AFM).

Dr. Pola serves as reviewer for the following scientific journals:

  • American Journal of Medical Genetics
  • American Journal of Hypertension
  • Annals of Neurology
  • Arteriosclerosis, Thrombosis, and Vascular Biology
  • Atherosclerosis
  • Brain Research
  • British Journal of Pharmacology
  • Circulation
  • Circulation Research
  • Cytotherapy
  • Diabetes
  • European Heart Journal
  • European Journal of Endocrinology
  • European Journal of Neurology
  • Experimental Neurology
  • Haematologica
  • Journal of Biological Chemistry
  • Journal of Cellular and Molecular Medicine
  • Journal of Cerebral Blood Flow and Metabolism
  • Journal of Human Hypertension
  • Journal of Thrombosis and Haemostasis
  • Neurology
  • Neuroscience Letters
  • Pharmacogenetics
  • PLoS One
  • Stroke
  • Thrombosis and Haemostasis

Funding History as Principal Investigator:

2008 – 2010 Grant number: 1R21HL089684
Title: Sonic muscle regeneration
Source: NIH-NHLBI   |   Type of grant: R21
Amount: $ 275,000
2008 – 2010 Grant number: RC23758V
Title: Angiogenic and vasculogenic effects of combined intramuscular endothelial progenitor cells and Sonic Hedgehog (Shh) gene therapy in peripheral ischemia
Source: Fondazione Roma   |   Type of grant: donation
Amount: € 158.600
2010 Charlton Family Grant
Title: Role of Sonic hedgehog in the hypoxic cerebellum
Source: Tufts University School of Medicine   |   Type of grant: intramural grant
Amount: $ 9,000
2009 – 2013 Grant number: RBID08MAFS
Title: Reactivation of the embryonic Sonic hedgehog signaling pathway for adult skeletal muscle regeneration
Source: Italian Department of University and Scientific Research (MIUR)   |   Type of Grant: FIRB IDEAS
Amount: € 1.116.000
2012 – 2015 Grant number: GR-2010-20305041
Title: Impaired Angiogenesis: a novel player and potential therapeutic target in Muscular Dystrophy
Source: Italian Department of Health   |   Type of Grant: Young Investigator Award
Amount: € 454.800

Selected Publications: